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FDA clears Lilly’s Olumiant for teens with severe alopecia areata
Company News

FDA clears Lilly’s Olumiant for teens with severe alopecia areata

INVESTING.COM

Eli Lilly and Company (LLY) said the U.S. Food and Drug Administration approved Olumiant (baricitinib) as a once-daily oral treatment for patients 12 years of age and older with severe alopecia areata (AA), expanding the drug’s existing U.S. label beyond adult use.

The approval is based on 36-week data from the BRAVE-AA-PEDS Phase 3 trial, which enrolled adolescents ages 12 to under 18. At baseline, the median Severity of Alopecia Tool (SALT) score was 100, indicating complete scalp hair loss, and patients had been living with AA for a mean of 6.4 years.

At week 36, 42% of patients receiving Olumiant 4 mg and 27% receiving Olumiant 2 mg achieved at least 80% scalp hair coverage, compared with 5% in the placebo group. At least 90% scalp hair coverage was achieved by 37% of patients on 4 mg and 21% on 2 mg, versus 2% on placebo. Patients treated with the 4 mg dose also showed improved eyebrow and eyelash coverage.

The recommended starting dose is 2 mg per day, with an option to increa

How Syracuse's Semiconductor Gamble May Help Save the Rust Belt
Company News

How Syracuse's Semiconductor Gamble May Help Save the Rust Belt

FINANCE.YAHOO.COM

What does it actually take to bring a Rust Belt city back to life? Micron is building one of the largest semiconductor factories in US history in Syracuse, a city that experienced major job loss after companies including GE, Carrier and General Motors left the area. Rob Simpson of CenterState CEO explains what attracted Micron to the city, local business owner Darin Price talks about what the investment means on the ground, and Brookings economist Joseph Parilla makes the case that Syracuse could be a model for reindustrialization across America.

This is a story about comebacks. About 250 miles northwest of the hustle and bustle of New York City lies Syracuse, New York. It's home to a major university named for the city, and once also counted major manufacturing companies like Carrier and General Electric among its residents. But in recent times, while the university has remained, many of the manufacturers have moved on, along with their jobs.

The entire Upstate New York corridor is

This may be the ‘missing piece’ for investors looking to boost AI exposure
Analyst & Opinion

This may be the ‘missing piece’ for investors looking to boost AI exposure

CNBC.COM

Investors looking to boost their exposure to artificial intelligence should target China, according to Matthews Asia portfolio manager Andrew Mattock.

He said investors will need a more deliberate approach because broad emerging market strategies won’t be that effective.

“Investors need to be aware when they buy an emerging market fund or when they buy a plain vanilla MSCI product… they’re not getting a lot of it,” Mattock told CNBC’s “ETF Edge” this week. “The big piece that you are missing… is the Chinese piece.”

He noted that companies from South Korea and Taiwan comprise almost half of the iShares MSCI Emerging Markets ETF (EEM) while the iShares MSCI China ETF (MCHI) lacks a focus on AI stocks.

Mattock is behind the Matthews China Fund (MCHFX). The fund invests at least 80% of its net assets in the common and preferred stocks of companies located in China, according to the firm’s website.

The fund is off 4% so far this year, as of Friday’s close. Its largest holdings include

Citigroup targets over $3 billion Banamex IPO for January - Bloomberg
Company News

Citigroup targets over $3 billion Banamex IPO for January - Bloomberg

INVESTING.COM

Investing.com -- Citigroup (NYSE:C) is lining up major Wall Street banks for an initial public offering of Mexico’s Grupo Financiero Banamex that could raise more than $3 billion, Bloomberg reported exclusively, citing people familiar with the matter.

Citigroup is expected to lead the offering, with Bank of America (NYSE:BAC), Goldman Sachs (NYSE:GS) and JPMorgan Chase (NYSE:JPM) also working on the transaction. Citigroup and Banamex are targeting January for the listing, according to the report.

The banks are still assessing how much of Citigroup’s remaining Banamex stake could be sold before the IPO. Smaller stake sales could take place ahead of the listing, the people said.

Plans remain under discussion, meaning details could change and more banks could join the group handling the offering. Representatives for Citigroup, Banamex, Bank of America, Goldman Sachs and JPMorgan declined to comment to Bloomberg.

The planned IPO forms part of Citigroup Chief Executive Jane Fraser’s bro

General Dynamics director Robert Steel sells $2.57m in stock
Company News

General Dynamics director Robert Steel sells $2.57m in stock

INVESTING.COM

Robert K. Steel, a director at General Dynamics Corp (NYSE:GD), sold 7,440 shares of the company’s common stock on September 23, 2026, for a total value of $2,574,619. The shares were sold at prices ranging from $345.824 to $346.119 per share.

The sale followed Mr. Steel’s acquisition of an equal number of shares through the exercise of stock options on the same day. He acquired 7,440 shares of General Dynamics common stock at a total cost of $1,574,211, with exercise prices ranging from $168.56 to $274.51 per share. The aerospace and defense giant currently trades at $336.72 with a market capitalization of $90.85 billion. According to InvestingPro analysis, the stock appears undervalued relative to its Fair Value, placing it among companies on the most undervalued list.

The exercised options had various vesting schedules, with some becoming exercisable as early as March 2023 and others as late as March 2027. Following these transactions, Mr. Steel directly owns 3,096 shares of Gener

Why Xi believes the U.S. and China can overcome the ‘Thucydides Trap’
Macro News

Why Xi believes the U.S. and China can overcome the ‘Thucydides Trap’

CNBC.COM

BEIJING — China is embracing the idea of competition without confrontation, by invoking an academic concept.

“The Thucydides Trap can be overcome,” Chinese President Xi Jinping said on arriving at the White House to meet U.S. President Donald Trump on Thursday, according to the Chinese side’s official readout.

That framing contrasts with the rhetorical question he posed at the May summit of whether the two countries could avoid the Thucydides Trap.

The Thucydides Trap, popularized by Harvard professor Graham Allison in the early 2010s, refers to how tensions between a rising and ruling power have historically often resulted in a war.

Thucydides was an Athenian general in ancient Greece. His historical record of the Peloponnesian War described how Athens’ rapid rise in power alarmed Sparta and made war between the two city-states inevitable.

Allison has met Xi and visited China multiple times, including in June 2026 for a World Economic Forum event. Allison was founding dean of Har

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Circle Internet Group (CRCL) stock fell 2.6% in extended trading after CFO Jeremy Fox-Geen and co-founder Sean Neville announced their departures 🔗. Fox-Geen, who oversaw a $1.2 billion IPO, will receive a $1.05 million severance package. While characterized as amicable, these executive transitions introduce short-term governance headwinds for the stablecoin provider as it navigates evolving digital asset regulations 🔗. Investors will monitor the company's executive search and operational continuity. #CRCL #Crypto #Fintech #ExecutiveChange

Circle stock dips as CFO Fox-Geen steps down and co-founder leaves board

Circle stock dips as CFO Fox-Geen steps down and co-founder leaves board

INVESTING.COMSep 25, 8:31 PM UTC
Stablecoin firm Circle finance chief Fox-Geen to step down

Stablecoin firm Circle finance chief Fox-Geen to step down

INVESTING.COMSep 25, 10:13 PM UTC
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Humana Inc. (HUM) shares jumped 6% today after Barclays upgraded the health insurer to Overweight from Equal-Weight. The upgrade is driven by increased conviction in Humana's upcoming Medicare Star ratings, with Barclays raising the probability of a key contract (H5216, covering 2.4M lives) achieving bonus status to 75%. This contract is critical for Humana's 2028 EPS target, representing an estimated $1.5 billion of EBIT and $9 of EPS. The Medicare Star ratings release is expected around October 8th 🔗.

Humana surges: Barclays bets big on Medicare star ratings rebound

Humana surges: Barclays bets big on Medicare star ratings rebound

STREETINSIDER.COMSep 25, 6:35 PM UTC
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A federal appeals court upheld the Department of War's decision to remove AI developer Anthropic (ANTP) from its supply chain due to usage restrictions on its Claude AI model 🔗. This ruling highlights growing tensions between AI developers and government demands for unrestricted use, particularly in military applications.

Separately, Microsoft co-founder Bill Gates is advocating for strict federal AI regulation, warning of the technology's potential for mass casualties in the wrong hands 🔗. These developments signal an accelerating push for AI governance and could impact future AI development and deployment across sectors.

Anthropic supply-chain designation upheld in AI military dispute

Anthropic supply-chain designation upheld in AI military dispute

STREETINSIDER.COMSep 25, 6:04 PM UTC
Bill Gates demands federal AI guardrails, warns of "a billion deaths"

Bill Gates demands federal AI guardrails, warns of "a billion deaths"

INVESTING.COMSep 25, 3:26 PM UTC
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The AI infrastructure buildout continues to drive market activity, with several companies benefiting from significant deals and bullish analyst sentiment:

  • Anthropic's $11.6B Computing Deal: European AI-linked stocks, including ASML, Infineon, and STMicroelectronics, rallied following Anthropic's massive computing deal, signaling sustained demand for AI hardware 🔗.
  • Data Center Expansion: Cipher Digital (CIFR) surged 5.9% after extending its Barber Lake data center lease to 20 years, boosting contracted revenue to over $9 billion with a commitment from a leading AI lab 🔗. Atlas Energy Solutions (AESI) jumped 13% on new power equipment deals for AI data centers 🔗.
  • AI Optical Growth: Mizuho initiated coverage on Tower Semiconductor (TSEM) with an Outperform rating and $300 price target, highlighting its leadership in silicon photonics chips crucial for AI data center connectivity 🔗.

This trend underscores the ongoing investment and expansion in the AI ecosystem, from chip manufacturing to data center power and infrastructure.

European AI-linked stocks rally After Anthropic’s $11.6 bln computing deal

European AI-linked stocks rally After Anthropic’s $11.6 bln computing deal

STREETINSIDER.COMSep 25, 11:54 AM UTC
Cipher Digital stock jumps after extending Barber Lake lease

Cipher Digital stock jumps after extending Barber Lake lease

STREETINSIDER.COMSep 25, 11:54 AM UTC
Atlas Energy stock surges on AI data center power deals

Atlas Energy stock surges on AI data center power deals

STREETINSIDER.COMSep 25, 12:49 PM UTC
Mizuho bullish on Tower Semiconductor, points to AI optical growth

Mizuho bullish on Tower Semiconductor, points to AI optical growth

STREETINSIDER.COMSep 25, 3:27 PM UTC
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The AI infrastructure buildout is accelerating, with European AI-linked stocks rallying after Anthropic signed an $11.6 billion computing deal 🔗. This follows a prior $1.8 billion agreement, highlighting growing demand for AI software and computing capacity 🔗.

In the US, data center and power infrastructure providers are also seeing significant activity:

  • Atlas Energy Solutions (AESI) jumped 13% premarket on new power equipment deals with a frontier AI lab for data center projects, including 283MW of incremental power generation 🔗.
  • Cipher Digital (CIFR) rose 5.9% after extending its Barber Lake data center lease to 20 years, increasing total contracted revenue to over $9 billion, driven by a binding commitment from a leading AI lab 🔗.

This trend underscores the massive capital expenditure flowing into AI infrastructure, driving demand for chips, power, and data center capacity.

European AI-linked stocks rally After Anthropic’s $11.6 bln computing deal

European AI-linked stocks rally After Anthropic’s $11.6 bln computing deal

STREETINSIDER.COMSep 25, 11:54 AM UTC
Atlas Energy stock surges on AI data center power deals

Atlas Energy stock surges on AI data center power deals

STREETINSIDER.COMSep 25, 12:49 PM UTC
Cipher Digital stock jumps after extending Barber Lake lease

Cipher Digital stock jumps after extending Barber Lake lease

STREETINSIDER.COMSep 25, 11:54 AM UTC
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HSBC upgraded BP and TotalEnergies to 'Buy', raising price targets to 640p and €93 respectively, citing higher Brent crude, refining margin, and gas price forecasts. The bank increased 2026-28 EPS estimates across the sector by averages of 19-65% 🔗. Separately, UBS upgraded Glencore to 'Buy' with a 650p price target, driven by stronger Marketing division performance, rising commodity prices, and improved copper growth visibility. UBS raised Glencore's 2026-27 EBITDA estimates by 5-7% 🔗. These actions signal growing analyst confidence in the energy and commodities sector's earnings outlook.

HSBC shuffles oil stocks ratings, upgrades BP and TotalEnergies to Buy

HSBC shuffles oil stocks ratings, upgrades BP and TotalEnergies to Buy

STREETINSIDER.COMSep 25, 10:59 AM UTC
UBS upgrades Glencore as commodity gains boost earnings outlook

UBS upgrades Glencore as commodity gains boost earnings outlook

STREETINSIDER.COMSep 25, 10:58 AM UTC
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Prime Medicine Inc (NASDAQ: PRME) shares gained over 12% in after-hours trading following FDA clearance of its Investigational New Drug (IND) application for PM647 🔗.

PM647 is an in vivo gene editing therapy targeting Alpha-1 Antitrypsin Deficiency (AATD), designed to correct the E342K mutation in the SERPINA1 gene. The planned Phase 1/2 clinical trial will evaluate safety, tolerability, and preliminary efficacy in adults with AATD 🔗.

This marks the company's second regulatory milestone, following clearance for PM577a, and aims to address both liver and lung manifestations of AATD, a condition with no approved curative treatment for its underlying genetic cause 🔗.

Prime Medicine stock surges on FDA IND clearance

Prime Medicine stock surges on FDA IND clearance

STREETINSIDER.COMSep 24, 8:38 PM UTC
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UBS has initiated coverage on five AI data center colocation stocks with 'Buy' ratings, citing rapid growth potential due to accelerating AI adoption and constrained computing capacity 🔗.

Key Highlights:

  • Hut 8 Corp (HUT): Buy rating, $143 PT (45% upside), strong pipeline and value creation track record 🔗.
  • Terawulf Inc (WULF): Buy rating, $24 PT (41% upside), differentiating ability to convert brownfield sites 🔗.
  • Applied Digital Corp (APLD): Buy rating, $38 PT (35% upside), substantial 1.3 GW backlog 🔗.

Power access is noted as the primary limiting factor for scaling compute infrastructure. This analyst action signals strong conviction in the AI infrastructure sector's growth trajectory. 🔗

UBS initiates five AI Infrastructure stocks, sees 36% upside

UBS initiates five AI Infrastructure stocks, sees 36% upside

STREETINSIDER.COMSep 24, 7:25 PM UTC
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The race for AI infrastructure expands to space as Google (GOOGL) launches Project Suncatcher, deploying proprietary TPUs into Low Earth Orbit via SpaceX to bypass terrestrial energy and infrastructure constraints 🔗. Meanwhile, NVIDIA (NVDA) is named the exclusive chip supplier for SpaceX's ambitious orbital data center constellation, aligning interests with a sizable stake in SpaceX 🔗.

Separately, UBS initiates coverage on five AI data center colocation stocks with bullish ratings, citing rapid growth potential and constrained computing capacity. Hut 8 Corp (HUT) receives a Buy rating and $143 PT (45% upside), Terawulf Inc (WULF) a Buy with $24 PT (41% upside), and Applied Digital Corp (APLD) a Buy with $38 PT (35% upside) 🔗. Everpure (P) also surged nearly 18% after raising its FY28 outlook, citing growth opportunities with hyperscalers 🔗.

NVIDIA and Alphabet emerge as top orbital chip beneficiaries

NVIDIA and Alphabet emerge as top orbital chip beneficiaries

INVESTING.COMSep 24, 5:02 PM UTC
Google to test custom AI chips in space on upcoming SpaceX mission

Google to test custom AI chips in space on upcoming SpaceX mission

STREETINSIDER.COMSep 24, 3:27 PM UTC
UBS initiates five AI Infrastructure stocks, sees 36% upside

UBS initiates five AI Infrastructure stocks, sees 36% upside

STREETINSIDER.COMSep 24, 7:25 PM UTC
Everpure Stock Leads S&P 500 Gainers After Rosy Outlook on AI Demand

Everpure Stock Leads S&P 500 Gainers After Rosy Outlook on AI Demand

INVESTOPEDIA.COMSep 24, 3:48 PM UTC
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Meta Platforms (META) is seeing renewed analyst confidence following its Connect conference. JPMorgan raised its price target to $920 from $820, citing the potential for its Muse AI agent to become a leading consumer AI application. New partnerships with Walmart, Best Buy, and Dick's Sporting Goods will enable shopping through Muse, potentially tapping into a $30 trillion agentic shopping market. The company also unveiled new smart glasses and a $1,299 VR headset, expanding its AI and hardware ecosystem. 🔗

Meta Made a Number of AI Announcements Last Night. Here’s What Analysts Have to Say About Them

Meta Made a Number of AI Announcements Last Night. Here’s What Analysts Have to Say About Them

INVESTOPEDIA.COMSep 24, 4:06 PM UTC
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